PlumCare DNA Advisor

  • DNAadvisor
  • Testimonial -1
  • DNAadvisor
  • Testimonial -1

Achieving a more definitive insight through the family genetic test in the Philippines

Proudly brought to you by Genscreen® in partnership with PlumCare, PlumCare DNA Advisor offers family genetic testing for your family members. By cross-analyzing the genetic information within your family, we can then help you better understand the significance any particular genetic variant may have on your family’s health.

Unlike other genetic tests, PlumCare DNA Advisor only requires saliva and does not cause any discomfort to your family.

Why choose DNA Advisor?
PlumCare DNA Advisor Family Trio Testing

Sequencing approximately 20,000 genes for variants associated with hundreds of health conditions that can be managed

PlumCare DNA Advisor can help provide information on your family's risk for various health conditions.

Hereditary predisposition to cancer

Hereditary predisposition to cancer

Hereditary cardiac conditions

Hereditary cardiac conditions

Hereditary connective tissue conditions

Hereditary connective tissue conditions

Anesthesia complications

Anesthesia complications

Hereditary predisposition to seizures

Hereditary predisposition to seizures
(Child only)

Hereditary hearing loss

Hereditary hearing loss
(Child only)

Hereditary metabolic conditions

Hereditary metabolic conditions

Understanding your DNA for disease prevention and management

You will receive personalized insights to help you understand and address the relationship between genetics and health. These insights can assist you to make informed decisions on your health. Should pathogenic or likely pathogenic variants be found, a personalized genetic counseling session with one of our certified genetic counselors will be available to you.

Tested and analyzed entirely by experts in the United States

Your family’s DNA samples will be sequenced by a CAP-accredited clinical laboratory in the United States, one of the most highly recognized standards for clinical laboratory testing performed on humans. Through the sequences, identifications of potentially disease-causing variants are performed using the most advanced bioinformatics tools.

Expert Report

Test Methodology & Limitations
Using genomic DNA from the submitted specimen(s), the SeqCap EZ Exome v2 was used to target the exon regions of the genome(s). These targeted regions were sequenced using the Illumina HiSeq 4000 sequencing system. The DNA sequence was mapped to and analyzed in comparison with the published human genome build UCSC hg19 reference sequence. The targeted coding exons and splice junctions of the known protein-coding RefSeq genes were assessed for the average depth of coverage and data quality threshold values.

The sequencing technology used generally allows for the identification of variants across at least 93% of the bases targeted in the exome. Variations in DNA capture performance, as well technological limitations with sequencing, may not allow the calling of variants across all DNA bases in the exome. Actual performance is variable. Some types of genomic changes will not be detected in this test, including copy number variants, mosaicism, and large scale structural variants such as translocations.

Accuracy of insertion and deletion calling is generally lower than single base variant calling. Variant interpretation is valid for the date of the report, and may change given updated information or published literature. This report is not diagnostic; genetic counseling and other medical follow-up is recommended to assess the risk to develop health conditions. Conditions studied in the panels may have other causes in addition to genetics. Depending on the source of client DNA, we may have sequenced non-germline DNA. PlumCare guarantees correct sample handling from point of receipt of client DNA only.

The Plumcare DNA Advisor service is brought to you by Genscreen® in partnership with PlumCare.